A Simplified Procedure for Indole Alkaloid Extraction from Catharanthus roseus Combined with a Semi-synthetic Production Process for Vinblastine.docVIP

Molecules 2007, 12, 1307-1315 molecules ISSN 1420-3049 ? 2007 by MDPI /molecules Full Paper A Simplified Procedure for Indole Alkaloid Extraction from Catharanthus roseus Combined with a Semi-synthetic Production Process for Vinblastine Arvind Verma 1,2,*, Into Laakso 2,*, Tuulikki Sepp?nen-Laakso 3, Aarre Huhtikangas 2 and Marja-Liisa Riekkola 1 1 Laboratory of Analytical Chemistry, Department of Chemistry, P.O. Box 55, 00014 University of Helsinki, Finland; Tel: +358919150252, Fax: +358919150253, E-mails: arvind.verma@helsinki.fi, marja-liisa.riekkola@helsinki.fi 2 Division of Phar