原创力文档Abuse risks and routes of administration of different prescription opioid compounds and formulations.docVIP
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Abuse risks and routes of administration of different prescription opioid compounds and formulations
Butleretal.HarmReductionJournal2011,8:29
/content/8/1/29
RESEARCH
OpenAccess
Abuserisksandroutesofadministrationof
differentprescriptionopioidcompoundsand
formulations
StephenFButler*,RyanABlack,TheresaACassidy,TarynMDaileyandSimonHBudman
Abstract
Background:Evaluationoftamperresistantformulations(TRFs)andclasswideRiskEvaluationandMitigation
Strategies(REMS)forprescriptionopioidanalgesicswillrequirebaselinedescriptionsofabusepatternsofexisting
opioidanalgesics,includingtherelativeriskofabuseofexistingprescriptionopioidsandcharacteristicpatternsof
abusebyalternateroutesofadministration(ROAs).
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