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Acne vulgaris, probiotics and the gut-brain-skin axis - back to the future
BoweandLoganGutPathogens2011,3:1
/content/3/1/1
REVIEW
OpenAccess
Acnevulgaris,probioticsandthegut-brain-skin
axis-backtothefuture?
WhitneyPBowe1*,AlanCLogan2*
Abstract
Over70yearshavepassedsincedermatologistsJohnH.StokesandDonaldM.Pillsburyfirstproposeda
gastrointestinalmechanismfortheoverlapbetweendepression,anxietyandskinconditionssuchasacne.Stokes
andPillsburyhypothesizedthatemotionalstatesmightalterthenormalintestinalmicroflora,increaseintestinal
permeabilityandcontributetosystemicinflammation.AmongtheremediesadvocatedbyStokesandPillsbury
wereLactobacillusacidophiluscultures.Manyaspects
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