Activated protein C for H1N1 influenza More work to do!.docVIP

LaRosa Critical Care 2010,14:156 /content/14/3/156 COMMENTARY Activated protein C for H1N1 in? uenza? More work to do! Steven P LaRosa* See related research by Schouten et al., /content/14/2/R65 distress syndrome? If so, does activated protein C (APC) Abstract – a molecule with anti coagulant, anti-in? ammatory and An animal model of H1N1 in?uenza demonstrates that this infection is associated with pulmonary and systemic activation of coagulation and impairment of ?brinolysis in addition to systemic in?ammation and intense neutrophil in?ux into the lung. Activated protein C attenuates coa