Activities of asymmetric dimethylarginine-related enzymes in white adipose tissue are associated with circulating lipid biomarkers.docVIP
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Activities of asymmetric dimethylarginine-related enzymes in white adipose tissue are associated with circulating lipid biomarkers
IwasakiDiabetologyMetabolicSyndrome2012,4:17
/content/4/1/17
DIABETOLOGY
METABOLIC SYNDROME
SHORT REPORT
OpenAccess
Activitiesofasymmetricdimethylarginine-related
enzymesinwhiteadiposetissueareassociated
withcirculatinglipidbiomarkers
HiroakiIwasaki1,2*
Abstract
Background:AsymmetricNG,NG-dimethylarginine(ADMA),anendogenousinhibitorofnitricoxidesynthase,is
regulatedbytheenzymaticparticipantsofsyntheticandmetabolicprocesses,i.e.,typeIproteinN-arginine
methyltransferase(PRMT)anddimethylargininedimethylaminohydrolase(DDAH).Previousreportshave
demonstratedthatcirculatingADMAlevelscanvaryinpati
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