Adipocyte mitochondrial genes and the forkhead factor FOXC2 are decreased in type 2 diabetes patients and normalized in response to rosiglitazone.docVIP

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Adipocyte mitochondrial genes and the forkhead factor FOXC2 are decreased in type 2 diabetes patients and normalized in response to rosiglitazone.doc

Adipocyte mitochondrial genes and the forkhead factor FOXC2 are decreased in type 2 diabetes patients and normalized in response to rosiglitazone

H?kanssonetal.DiabetologyMetabolicSyndrome2011,3:32 /content/3/1/32 DIABETOLOGY METABOLIC SYNDROME RESEARCH OpenAccess Adipocytemitochondrialgenesandtheforkhead factorFOXC2aredecreasedintype2diabetes patientsandnormalizedinresponseto rosiglitazone JoakimH?kansson1,2*,Bj?rnEliasson3,UlfSmith3andSvenEnerb?ck1 Abstract Background:FOXC2haslatelybeenimplicatedindiabetesandobesityaswellasmitochondrialfunctionand biogenesisandalsoasaregulatorofmtTFA/Tfam.Inthisstudy,theexpressionofFOXC2andselectedgenes involvedinmitochondrialfunctionandbiogenesisinhealthysubjectsandinamatchedcohortwithtype2 diabe

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Adipocyte mitochondrial genes and the forkhead factor FOXC2 are decreased in type 2 diabetes patients and normalized in response to rosiglitazone.docVIP