Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation a basic science study.docVIP

Available online /content/9/6/R121 Research article Open Access Vol 9 No 6 Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study Christelle Boileau1, Nathalie Amiable1, Johanne Martel-Pelletier1, Hassan Fahmi1, Nicolas Duval2 and Jean-Pierre Pelletier1 1Osteoarthritis Research Unit, University of Montreal Hospital Centre, Notre-Dame Hospital, 1560 Sherbrooke Street East, Montreal, Quebec, H2L 4M1, Canada 2Pavillon des Charmilles, 1487, boul. des Lau