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An fMRI study of unconditioned responses in post-traumatic stress disorder
Linnmanetal.BiologyofMoodAnxietyDisorders2011,1:8
/content/1/1/8
Biology of
Mood Anxiety Disorders
RESEARCH
OpenAccess
AnfMRIstudyofunconditionedresponsesin
post-traumaticstressdisorder
ClasLinnman1*,ThomasAZeffiro2,RogerKPitman1andMohammedRMilad1
Abstract
Background:Bothfearandpainprocessingarealteredinpost-traumaticstressdisorder(PTSD),asevidencedby
functionalneuroimagingstudiesshowingincreasedamygdalaresponsestothreats,andincreasedinsula,putamen
andcaudateactivityinresponsetoheatpain.Usingpsychophysiologyandfunctionalmagneticresonance
imaging,westudiedconditionedandunconditionedautonomi
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