原创力文档An open pilot study of zonisamide augmentation in major depressive patients not responding to a low dose trial with duloxetine preliminary results on tolerability and clinical effects.docVIP
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An open pilot study of zonisamide augmentation in major depressive patients not responding to a low dose trial with duloxetine preliminary results on tolerability and clinical effects
Fornaroetal.AnnalsofGeneralPsychiatry2011,10:23
/content/10/1/23
PRIMARY RESEARCH
OpenAccess
Anopenpilotstudyofzonisamideaugmentation
inmajordepressivepatientsnotrespondingtoa
lowdosetrialwithduloxetine:preliminaryresults
ontolerabilityandclinicaleffects
MicheleFornaro1,MatteoMartino1*,BrunaDalmasso2,SalvatoreColicchio3,MarziaBenvenuti4,GiulioRocchi1,
AndreaEscelsior1andGiulioPerugi4
Abstract
Background:Despitemultipleantidepressantoptions,majordepressivedisorder(MDD)stillfaceshighnon-
responserates,eventuallyrequiringanticonvulsantaugmentationstrategiestoo.Theaimofthisstudywasto
exploresuc
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