Antiparkinson Prodrugs.docVIP

Molecules 2008, 13, 46-68 molecules ISSN 1420-3049 ? 2008 by MDPI /molecules Review Antiparkinson Prodrugs Antonio Di Stefano*, Piera Sozio and Laura Serafina Cerasa Department of Drug Sciences, “G. dAnnunzio” University, School of Pharmacy, Via dei Vestini 31, 66100 Chieti, Italy * Author to whom correspondence should be addressed. Tel.: +39-871-3554708; fax: +39-871- 3554706; E-mail: adistefano@unich.it Received: 4 December 2007; in revised form: 11 January 2008 / Accepted: 11 January 2008 / Published: 16 January 2008 Abstract: Parkinson’s disease (PD) is a progressive, neurodegene