原创力文档Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data.docVIP
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Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data
Parkeretal.GenomeBiology2012,13:R113
/2012/13/12/R113
RESEARCH
OpenAccess
AssessingtelomericDNAcontentinpediatric
cancersusingwhole-genomesequencingdata
MatthewParker1,XiangChen1,ArmitaBahrami2,JamesDalton2,MichaelRusch1,GangWu1,JohnEaston3,
Nai-KongCheung4,MichaelDyer5,ElaineRMardis6,7,RichardKWilson6,7,CharlesMullighan2,RichardGilbertson5,
SuzanneJBaker5,GerardZambetti8,DavidWEllison2,JamesRDowning2andJinghuiZhang1* ,for
thePediatricCancerGenomeProject
Abstract
Background:TelomeresaretheprotectivearraysoftandemTTAGGGsequenceandassociatedproteinsatthe
terminiofchromosomes.Telomeresshortenat
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