分子生物学（张海红）11 章Site-Specific Recombination.pptVIP

* Site-specific recombination differs from general recombination in that short specific sequences which are required for the recombination, are the only sites at which recombination occurs. These reactions invariably require specialized proteins to recognize these sites and to catalyze the recombination reaction at these sites. The steps and features of the general recombination reaction, however, still apply: strand exchange formation of a Holliday intermediate branch migration resolution. * * The chromosomes of most bacteria, plasmids and some viral genomes are circular. * * As a resul