Bench-to-bedside review High-mobility group box 1 and critical illness.docVIP

Available online /content/11/5/229 Review Bench-to-bedside review: High-mobility group box 1 and critical illness Mitchell P Fink Departments of Critical Care Medicine, Surgery and Pharmacology, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA Corresponding author: Mitchell P Fink, fink.mp@ Published: 19 September 2007 Critical Care 2007, 11:229 (doi:10.1186/cc6088) This article is online at /content/11/5/229 ? 2007 BioMed Central Ltd Abstract HMG1 box contains a string of 70 to 80 amino acid residues, which is folded into a characteristic, twisted, L-