Bench-to-bedside review Vasopressin in the management of septic shock.docVIP

Russell Critical Care 2011,15:226 /content/15/4/226 RE VIE W Bench-to-bedside review: Vasopressin in the management of septic shock James A Russell* Abstract This review of vasopressin in septic shock di?ers from previous reviews by providing more information on the physiology and pathophysiology of vasopressin and vasopressin receptors, particularly because of recent interest in more speci?c AVPR1a agonists and new information from the Vasopressin and Septic Shock Trial (VASST), a randomized trial of vasopressin versus norepinephrine in septic shock. Relevant literature regarding vasopres