Bootstrapping of gene-expression data improves and controls the false discovery rate of differentially expressed genes.docVIP

Genet.Sel.Evol.36(2004)191–205
c INRA,EDPSciences,2004 DOI:10.1051/gse:2003058 191 Originalarticle Bootstrappingofgene-expressiondata improvesandcontrolsthefalsediscovery rateofdi?erentiallyexpressedgenes TheoH.E.M????????a?,MikeE.G??????b a InstituteforAnimalScience,AgriculturalUniversityofNorway,1432?s,Norway b InstituteofLandandFoodResources,UniversityofMelbourne,Parkville,3052Australia, andVictorianInstituteofAnimalScience,Attwood,Victoria,3049Australia (Received17December2002;accepted23October2003) Abstract– Theordinary-,penalized-,andbootstrapt-test,leastsquaresandbestlinearunbi- ased