Caveats of chronic exogenous corticosterone treatments in adolescent rats and effects on anxiety-like and depressive behavior and hypothalamic-pituitary-adrenal (HPA) axis function.docVIP
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Caveats of chronic exogenous corticosterone treatments in adolescent rats and effects on anxiety-like and depressive behavior and hypothalamic-pituitary-adrenal (HPA) axis function
WatersandMcCormickBiologyofMoodAnxietyDisorders2011,1:4
/content/1/1/4
Biology of
Mood Anxiety Disorders
RESEARCH
OpenAccess
Caveatsofchronicexogenouscorticosterone
treatmentsinadolescentratsandeffectson
anxiety-likeanddepressivebehaviorand
hypothalamic-pituitary-adrenal(HPA)axisfunction
PattiWatersandCherylMMcCormick*
Abstract
Background:Administrationofexogenouscorticosteroneisaneffectivepreclinicalmodelofdepression,butits
usehasinvolvedprimarilyadultrodents.Usingtwodifferentproceduresofadministrationdrawnfromthe
literature,weexploredthepossibilityofexogenouscorticosteronemodelsinadolesc
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