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CD163 versus CD68 in tumor associated macrophages of classical hodgkin lymphoma
Harrisetal.DiagnosticPathology2012,7:12
/content/7/1/12
RESEARCH
OpenAccess
CD163versusCD68intumorassociated
macrophagesofclassicalhodgkinlymphoma
JonathanAHarris1*,SalviaJain2,QinghuRen1,AlirezahZarineh1,CynthiaLiu1andSherifIbrahim1
Abstract
ClassicalHodgkinlymphoma(CHL)isaB-celllymphoproliferativedisorderwitharelativelygoodprognosis.Asmall
butsignificantpercentageofpatients,however,willrespondpoorlytotherapy.Arecentgeneexpressionprofiling
studyhasidentifiedamacrophagesignaturewhichhasbeencorrelatedwithprimarytreatmentfailure,and
immunohistochemicaltissuemicroarrayforCD68wasshowntoreflecttheg
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