Cell fate decision T-helper 1 and 2 subsets in immune responses.docVIP

/content/2/3/179 Review Cell fate decision: T-helper 1 and 2 subsets in immune responses Chen Dong and Richard A Flavell Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, USA Received: 29 November 2000 Revisions requested: 7 January 2000 Revisions received: 7 February 2000 Accepted: 18 February 2000 Published: 27 March 2000 Arthritis Res 2000,2:179–188 The electronic version of this article can be found online at /content/2/3/179 ? Current Science Ltd Abstract After activation CD4+ helper T cells differentiate into T-helper (Th)1 or Th2 effector cel