Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia.docVIP
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Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia
Nerstingetal.ClinicalProteomics2011,8:8
/content/8/1/8
CLINICAL
PROTEOMICS
REVIEW
OpenAccess
Challengesinimplementingindividualized
medicineillustratedbyantimetabolitetherapy
ofchildhoodacutelymphoblasticleukemia
JacobNersting1,LouiseBorst1andKjeldSchmiegelow1,2*
*Correspondence:kjeld.
Abstract
schmiegelow@rh.regionh.dk
1PediatricOncologyResearch
Predictingtheresponsetomedicaltherapyandsubsequentlyindividualizingthe
treatmenttoincreaseefficacyorreducetoxicityhasbeenalongstandingclinical
goal.Notleastwithinoncology,wheremanypatientsfailtobecured,andothersare
treatedtoorbeyondthelimitofaccepta
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