Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia.docVIP

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Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia.doc

Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia

Nerstingetal.ClinicalProteomics2011,8:8 /content/8/1/8 CLINICAL PROTEOMICS REVIEW OpenAccess Challengesinimplementingindividualized medicineillustratedbyantimetabolitetherapy ofchildhoodacutelymphoblasticleukemia JacobNersting1,LouiseBorst1andKjeldSchmiegelow1,2* *Correspondence:kjeld. Abstract schmiegelow@rh.regionh.dk 1PediatricOncologyResearch Predictingtheresponsetomedicaltherapyandsubsequentlyindividualizingthe treatmenttoincreaseefficacyorreducetoxicityhasbeenalongstandingclinical goal.Notleastwithinoncology,wheremanypatientsfailtobecured,andothersare treatedtoorbeyondthelimitofaccepta

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