Changes in Astrocyte Shape Induced by Sublytic Concentrations of the Cholesterol-Dependent Cytolysin Pneumolysin Still Require Pore-Forming Capacity.docVIP

Toxins 2011, 3, 43-62; doi:10.3390/toxins3010043 OPEN ACCESS toxins ISSN 2072-6651 /journal/toxins Article Changes in Astrocyte Shape Induced by Sublytic Concentrations of the Cholesterol-Dependent Cytolysin Pneumolysin Still Require Pore-Forming Capacity Christina F?rtsch 1,?, Sabrina Hupp 1,?, Jiangtao Ma 2, Timothy J. Mitchell 2, Elke Maier 3, Roland Benz 3 and Asparouh I. Iliev 1,* 1 DFG Membrane, Cytoskeleton Interaction Group, Institute of Pharmacology and Toxicology Rudolf Virchow Center for Experimental Medicine, University of Würzburg, Versbacherstr. 9, 97078 Würzburg, Germany