Changes in pain and insulin-like growth factor 1 in fibromyalgia during exercise the involvement of cerebrospinal inflammatory factors and neuropeptides.docVIP
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Changes in pain and insulin-like growth factor 1 in fibromyalgia during exercise the involvement of cerebrospinal inflammatory factors and neuropeptides
Bjersingetal.ArthritisResearchTherapy2012,14:R162
/content/14/4/R162
RESEARCH ARTICLE
OpenAccess
Changesinpainandinsulin-likegrowthfactor1
infibromyalgiaduringexercise:theinvolvement
ofcerebrospinalinflammatoryfactorsand
neuropeptides
JanLBjersing1,2*,MatsDehlin1,2,MalinErlandsson1,MariaIBokarewa1,2 andKaisaMannerkorpi1,3
Abstract
Introduction:Fibromyalgia(FM)ischaracterizedbychronicpain.Impairedgrowthhormoneresponsesand
reducedseruminsulin-likegrowthfactor1(IGF-1)arecommoninFM.Theaimwastoexaminechangesinserum
IGF-1,cerebrospinalfluid(CSF),neuropeptides,andcytokinesduringaerobicexercis
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