Changes in pain and insulin-like growth factor 1 in fibromyalgia during exercise the involvement of cerebrospinal inflammatory factors and neuropeptides.docVIP

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Changes in pain and insulin-like growth factor 1 in fibromyalgia during exercise the involvement of cerebrospinal inflammatory factors and neuropeptides.doc

Changes in pain and insulin-like growth factor 1 in fibromyalgia during exercise the involvement of cerebrospinal inflammatory factors and neuropeptides

Bjersingetal.ArthritisResearchTherapy2012,14:R162 /content/14/4/R162 RESEARCH ARTICLE OpenAccess Changesinpainandinsulin-likegrowthfactor1 infibromyalgiaduringexercise:theinvolvement ofcerebrospinalinflammatoryfactorsand neuropeptides JanLBjersing1,2*,MatsDehlin1,2,MalinErlandsson1,MariaIBokarewa1,2 andKaisaMannerkorpi1,3 Abstract Introduction:Fibromyalgia(FM)ischaracterizedbychronicpain.Impairedgrowthhormoneresponsesand reducedseruminsulin-likegrowthfactor1(IGF-1)arecommoninFM.Theaimwastoexaminechangesinserum IGF-1,cerebrospinalfluid(CSF),neuropeptides,andcytokinesduringaerobicexercis

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