Changes of microRNAs-192, 196a and 203 correlate with Barretts esophagus diagnosis and its progression compared to normal healthy individuals.docVIP

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Changes of microRNAs-192, 196a and 203 correlate with Barretts esophagus diagnosis and its progression compared to normal healthy individuals.doc

Changes of microRNAs-192, 196a and 203 correlate with Barretts esophagus diagnosis and its progression compared to normal healthy individuals

Luznaetal.DiagnosticPathology2011,6:114 /content/6/1/114 RESEARCH OpenAccess ChangesofmicroRNAs-192,196aand203 correlatewithBarrett’sesophagusdiagnosisand itsprogressioncomparedtonormalhealthy individuals PavlaLuzna1,JanGregar2,IvoUberall3,LenkaRadova4,VlastimilProchazka2andJiriEhrmannJr1,3* Abstract Background:Barrett’sesophagus(BE)isadiseasewitharisingprevalenceinwesterncountriesprobablydueto theunhealthylifestyle.Insignificantnumberofcasesitdevelopstoesophagealadenocarcinoma.Twodecades ago,importantgeneregulators(microRNAs)werediscoveredandtheirattendanceintheprocessofmalignant transforma

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Changes of microRNAs-192, 196a and 203 correlate with Barretts esophagus diagnosis and its progression compared to normal healthy individuals.docVIP