Characteristics of CD8+ T cell subsets in Chinese patients with chronic HIV infection during initial ART.docVIP

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Characteristics of CD8+ T cell subsets in Chinese patients with chronic HIV infection during initial ART.doc

CharacteristicsofCD8TcellsubsetsinChinesepatientswithchronicHIVinfectionduringinitialART

Jiaoetal.AIDSResearchandTherapy2011,8:15 /content/8/1/15 RESEARCH OpenAccess CharacteristicsofCD8+TcellsubsetsinChinese patientswithchronicHIVinfectionduringinitial ART YanmeiJiao?,WeiHua?,TongZhang,YonghongZhang,YunxiaJi,HongweiZhang*andHaoWu* Abstract Background:CD8+TcellsmayplayanimportantroleinprotectingagainstHIV.However,thechangesofCD8+T cellsubsetsduringearlyperiodofARThavenotbeenfullystudied. Methods:Twenty-oneasymptomatictreatment-naiveHIV-infectedpatientswithCD4T+cellslessthan350cells/μl wereenrolledinthestudy.Na?ve,centralmemory(CM),effectivememory(EM)andterminallydifferentiatedef

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