Chotosan (Diaoteng San)-induced improvement of cognitive deficits in senescence-accelerated mouse (SAMP8) involves the amelioration of angiogenicneurotrophic factors and neuroplasticity systems in the brain.docVIP
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Chotosan (Diaoteng San)-induced improvement of cognitive deficits in senescence-accelerated mouse (SAMP8) involves the amelioration of angiogenicneurotrophic factors and neuroplasticity systems in the brain
Zhaoetal.ChineseMedicine2011,6:33
/content/6/1/33
RESEARCH
OpenAccess
Chotosan(DiaotengSan)-inducedimprovement
ofcognitivedeficitsinsenescence-accelerated
mouse(SAMP8)involvestheameliorationof
angiogenic/neurotrophicfactorsand
neuroplasticitysystemsinthebrain
QiZhao1,2,TakakoYokozawa2,3,KoichiTsuneyama4,KenTanaka5,TakeshiMiyata6,7,NotoshiShibahara2and
KinzoMatsumoto1*
Abstract
Background:Chotosan(CTS,DiaotengSan),aKampomedicine(ieChinesemedicine)formula,isreportedly
effectiveinthetreatmentofpatientswithcerebralischemicinsults.Thisstudyaimstoevaluatethetherapeutic
potentialofCTSincognitivedef
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