原创力文档Clinical effectiveness of fresh frozen plasma compared with fibrinogen concentrate a systematic review.docVIP
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Clinical effectiveness of fresh frozen plasma compared with fibrinogen concentrate a systematic review
Kozek-Langeneckeretal.CriticalCare2011,15:R239
/content/15/5/R239
RESEARCH
OpenAccess
Clinicaleffectivenessoffreshfrozenplasma
comparedwithfibrinogenconcentrate:
asystematicreview
SibylleKozek-Langenecker1*,BennyS?rensen2,3,JohnRHess4andDonatRSpahn5
Abstract
Introduction:Haemostatictherapyinsurgicaland/ormassivetraumapatientstypicallyinvolvestransfusionoffresh
frozenplasma(FFP).PurifiedhumanfibrinogenconcentratemayofferanalternativetoFFPinsomeinstances.In
thissystematicreview,weinvestigatedthecurrentevidencefortheuseofFFPandfibrinogenconcentrateinthe
perioperativeormassivetraumasetting.
Meth
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