Clinical Management of HIV Drug Resistance.docVIP

Viruses 2011, 3, 347-378; doi:10.3390/v3040347 OPEN ACCESS viruses ISSN 1999-4915 /journal/viruses Review Clinical Management of HIV Drug Resistance Karoll J. Cortez and Frank Maldarelli * HIV Drug Resistance Program, NCI, NIH, Building 10 Rm 5A06, Bethesda, MD 20892, USA; E-Mail: karoll.cortez@ * Author to whom correspondence should be addressed; E-Mail: fmalli@; Tel.: +1-301-435-8019; Fax: +1-301-480-1735. Received: 9 March 2011 / Accepted: 30 March 2011 / Published: 14 April 2011 Abstract: Combination antiretroviral therapy for HIV-1 infection has resulted in profound reductions in