Clinical effectiveness of biologics in clinical practice.docVIP

Scott and Kingsley Arthritis Research Therapy 2010,12:115 /content/12/2/115 EDITORIAL Clinical e? ectiveness of biologics in clinical practice David L Scott* and Gabrielle Kingsley See related research by Wolfe and Michaud, /content/12/2/R35 Most evidence for using TNF inhibitors in active Abstract established RA comes from randomised controlled trials TNF inhibitors are currently considered both e?ective and cost-e?ective in patients with active (RCTs) in patients in whom methotrexate treatment has faile is evidence is supported by observational rheumatoid arthritis (RA), p