Clinical review Sepsis and septic shock - the potential of gene arrays.docVIP

Wong Critical Care 2012,16:204 /content/16/1/204 RE VIE W Clinical review: Sepsis and septic shock - the potential of gene arrays Hector R Wong* microarray approach, including limitations and study Abstract design considerations. Subsequently, the review will focus on the potential translational application of microarray data and genome-wide expression pro? ling to the sepsis ? eld. Four broad areas will be discussed: genome-level understanding of sepsis, biomarker discovery, gene expression-based identi? cation of septic shock subclasses, a