Clinicopathological significance of fascin and CD44v6 expression in endometrioid carcinoma.docVIP

Gunetal.DiagnosticPathology2012,7:80 /content/7/1/80 RESEARCH OpenAccess Clinicopathologicalsignificanceoffascinand CD44v6expressioninendometrioidcarcinoma BanuDoganGun*,BurakBahadir,SibelBektas,FigenBarut,GamzeYurdakan,NiluferOnakKandemir andSukruOguzOzdamar Abstract Background:FascinandCD44v6mayhavesignificantrolesasbiomarkersintumourprogressionandmetastasis. Inendometrioidcarcinomas,thefascinexpressionprofileislessdefined,andthesignificanceofCD44v6is uncertain.WeaimedtoinvestigatetheexpressionsofbothfascinandCD44v6inendometrioidcarcinomasandto evaluatetheirinter-relationwithclinicopathologi