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Control of viral replication after cessation of HAART.doc

Control of viral replication after cessation of HAART

VanGulcketal.AIDSResearchandTherapy2011,8:6 /content/8/1/6 CASE REPORT OpenAccess Controlofviralreplicationaftercessationof HAART EllenVanGulck1*,LeoHeyndrickx1,LotteBracke1,SandraCoppens1,EricFlorence2,AnneBuvé3,PaulLewi4, GuidoVanham1,5 Abstract WedescribetwopatientswhodidnotexperienceaviralreboundaftercessationofHAARTwhichwasinitiatedfor progressivedisease.CD4T-cellcountremainedstableinonepatientandprogressivelydeclinedintheother, despiteapparentviralcontrol.Wefailedtoidentifyanyimmuneactivationorgeneticmarkersthatcouldofferan explanationforthisunusual“secondarycontroller”status.Buttheirvir

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