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Correlating anterior insula gray matter volume changes in young people with clinical and neurocognitive outcomes an MRI study.doc

Correlating anterior insula gray matter volume changes in young people with clinical and neurocognitive outcomes an MRI study

Hattonetal.BMCPsychiatry2012,12:45 /1471-244X/12/45 RESEARCH ARTICLE OpenAccess Correlatinganteriorinsulagraymattervolume changesinyoungpeoplewithclinicaland neurocognitiveoutcomes:anMRIstudy SeanNHatton1,2*,JimLagopoulos1,DanielFHermens1,SharonLNaismith1,MaxwellRBennett1andIanBHickie1 Abstract Background:Theanteriorinsulacortexisconsideredtobeboththestructuralandfunctionallinkbetween experience,affect,andbehaviour.Magneticresonanceimaging(MRI)studieshaveshownchangesinanteriorinsula graymattervolume(GMV)inpsychosis,bipolar,depressionandanxietydisordersinolderpatients,butfewstudies haveinvesti

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