Distribution of serotonergic and dopaminergic nerve fibers in the salivary gland complex of the cockroach Periplaneta americana.docVIP
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Distribution of serotonergic and dopaminergic nerve fibers in the salivary gland complex of the cockroach Periplaneta americana
BMC Physiology
BMC2002Physiology,
2
Research article
x
Distribution of serotonergic and dopaminergic nerve fibers in the
salivary gland complex of the cockroach Periplaneta americana
Otto Baumann*1, Petra Dames1, Dana Kühnel1,2 and Bernd Walz1
Address: 1Institut für Biochemie und Biologie, Zoophysiologie, Universit?t Potsdam, Lennéstr. 7a, 14471 Potsdam, Germany and 2Institut für
Ern?hrungswissenschaft, Ern?hrungstoxikologie, Universit?t Potsdam, Arthur-Scheunert-Allee 114-116, 14558 Potsdam-Rehbrücke, Germany
E-mail: Otto Baumann* - obaumann@rz.uni-potsdam.de; Petra Dames - pittys@lycos.de; Dana Kühnel - Kuehnel@rz.uni-potsdam.de;
Bernd Walz - walz@rz.uni-potsdam.de
*Corresponding author
Published: 24 June 2002
Received: 12 March 2002
Accepted: 24 June 2002
BMC Physiology 2002, 2:9
This article is available from: /1472-6793/2/9
? 2002 Baumann et al; licensee BioMed Central Ltd. Verbatim copying and redistribution of this article are permitted in any medium for any purpose, pro-
vided this notice is preserved along with the articles original URL.
Abstract
Background: The cockroach salivary gland consists of secretory acini with peripheral ion-
transporting cells and central protein-producing cells, an extensive duct system, and a pair of
reservoirs. Salivation is controled by serotonergic and dopaminergic innervation. Serotonin
stimulates the secretion of a protein-rich saliva, dopamine causes the production of a saliva without
proteins. These findings suggest a model in which serotonin acts on the central cells and possibly
other cell types, and dopamine acts selectively on the ion-transporting cells. To examine this model,
we have analyzed the spatial relationship of dopaminergic and serotonergic nerve fibers to the
various cell types.
Results: The acinar tissue is entangled in a meshwork of serotonergic and dopaminergic varicose
fibers. Dopaminergic fibers reside only at the surface of the acini n
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