Effect of fluid resuscitation on mortality and organ function in experimental sepsis models.docVIP

下载本文档

1
0
约4.72万字
约 11页
2017-05-16 发布于上海
举报
版权申诉

Effect of fluid resuscitation on mortality and organ function in experimental sepsis models.doc

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Effect of fluid resuscitation on mortality and organ function in experimental sepsis models

Available online /content/13/6/R186 Research Open Access Vol 13 No 6 Effect of fluid resuscitation on mortality and organ function in experimental sepsis models Sebastian Brandt1, Tomas Regueira2*, Hendrik Bracht2*, Francesca Porta2, Siamak Djafarzadeh2, Jukka Takala2, José Gorrasi2, Erika Borotto2, Vladimir Krejci1, Luzius B Hiltebrand1, Lukas E Bruegger3, Guido Beldi3, Ludwig Wilkens5, Philipp M Lepper2, Ulf Kessler4 and Stephan M Jakob2 1Department of Anaesthesia and Pain Therapy, Inselspital, Bern University Hospital and University of Bern, CH-3010 Bern, Switzerland 2Department of Intensive Care Medicine, Inselspital, Bern University Hospital and University of Bern, CH-3010 Bern, Switzerland 3Department of Visceral and Transplant Surgery, Inselspital, Bern University Hospital and University of Bern, CH-3010 Bern, Switzerland 4Department of Pediatric Surgery, Inselspital, Bern University Hospital and University of Bern, CH-3010 Bern, Switzerl 5Institute of Pathology, University of Bern, Murtenstrasse 31, CH-3010 Bern, Switzerland * Contributed equally Corresponding author: Stephan M Jakob, Stephan.Jakob@insel.ch Received: 31 Jul 2009 Revisions requested: 21 Sep 2009 Revisions received: 12 Oct 2009 Accepted: 23 Nov 2009 Published: 23 Nov 2009 Critical Care 2009, 13:R186 (doi:10.1186/cc8179) This article is online at: /content/13/6/R186 ? 2009 Brandt et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Several recent studies have shown that a positive fluid balance in critical illness is associated with worse outcome. We tested the effects of moderate vs. high-volume resuscitation strategies on mortality, systemic and regional blood flows, Results Mortality in high-volume groups was 87% (peritoni