Evaluation of a commercial web-based weight loss and weight loss maintenance program in overweight and obese adults a randomized controlled trial.docVIP

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Evaluation of a commercial web-based weight loss and weight loss maintenance program in overweight and obese adults a randomized controlled trial.doc

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Evaluation of a commercial web-based weight loss and weight loss maintenance program in overweight and obese adults a randomized controlled trial

Collinsetal.BMCPublicHealth2010,10:669 /1471-2458/10/669 STUDY PROTOCOL OpenAccess Evaluationofacommercialweb-basedweight lossandweightlossmaintenanceprogramin overweightandobeseadults:arandomized controlledtrial ClareECollins1*,PhilipJMorgan2,PennieJones3,KateFletcher1,JuliaMartin1,ElroyJAguiar4,AshleeLucas4, MelindaNeve1,PatrickMcElduff5,RobinCallister4 Abstract Background:Obesityratesinadultscontinuetoriseandeffectivetreatmentprogramswithabroadreachare urgentlyrequired.Thispaperdescribesthestudyprotocolforaweb-basedrandomizedcontrolledtrial(RCT)ofa commerciallyavailableprogramforoverweightandobeseadultmalesandfemales.TheaimofthisRCTwasto determineandcomparetheefficacyoftwoweb-basedinterventionsforweightlossandmaintenanceoflost weight. Methods/Design:OverweightandobeseadultmalesandfemaleswerestratifiedbygenderandBMIandrandomly assignedtooneofthreegroupsfor12-weeks:waitlistcontrol,orbasicorenhancedonlineweight-loss.Control participantswerere-randomizedtothetwoweightlossgroupsattheendofthe12-weekperiod.Thebasicand enhancedgroupparticipantshadanoptiontocontinueorrepeatthe12-weekprogram.Iftheweightlossgoalwas achievedattheendof12,otherwiseoncompletionof24weeksofweightloss,participantswerere-randomizedto oneoftwoonlinemaintenanceprograms(maintenancebasicormaintenanceenhanced),until18monthsfrom commencingtheweightlossprogram.Assessmentstookplaceatbaseline,three,six,and18monthsafter commencingtheinitialweightlossinterventionwithcontrolparticipantsrepeatingtheinitialassessmentafterthree monthofwaiting.Theprimaryoutcomeisbodymassindex(BMI).Otheroutcomesincludeweight,waist circumference,bloodpressure,plasmamarkersofcardiovasculardiseaserisk,dietaryintake,eatingbehaviours, physicalactivityandqualityoflife. Boththeweightlossandmaintenanceoflostweightprogramswerebasedonsocialcognitivetheorywithpartici- pantsadvisedtosetgoals,self-monitorweight,dietaryintakeandphysicalactivitylevels.Theenhancedweight lossandmaintenanceprogramsprovidedadditionalpersonalized,system-generatedfee