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Expiratory automatic endotracheal tube compensation reduces dynamic hyperinflation in a physical lung model.doc

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Expiratory automatic endotracheal tube compensation reduces dynamic hyperinflation in a physical lung model

Available online /content/13/1/R4 Research Open Access Vol 13 No 1 Expiratory automatic endotracheal tube compensation reduces dynamic hyperinflation in a physical lung model Christoph Haberthür1, Annekathrin Mehlig1,2, John F Stover3, Stefan Schumann4, Knut M?ller4,5, Hans-Joachim Priebe4 and Josef Guttmann4 1Department of Anesthesiology, Section for Surgical Intensive Care, Kantonsspital Luzern, Spitalstrasse, CH-6000 Luzern, Switzerland 2Department of Internal Medicine, Kantonsspital Liestal, Rheinstrasse, CH-4410 Liestal, Switzerland 3Division of Surgical Intensive Care Medicine, University Hospital Zurich, R?mistrasse, CH-8091 Zürich, Switzerland 4Department of Anesthesiology, Section for Experimental Anesthesiology, University Medical Center Freiburg, Hugstetterstrasse, D-79106 Freiburg, Germany 5Biomedical Engineering, University of Applied Sciences, Campus Furtwangen, Robert-Gerwig-Platz, D-78120 Furtwangen, Germany Corresponding author: Christoph Haberthür, christoph.haberthuer@ksl.ch Received: 21 Aug 2008 Revisions requested: 16 Sep 2008 Revisions received: 9 Dec 2008 Accepted: 23 Jan 2009 Published: 23 Jan 2009 Critical Care 2009, 13:R4 (doi:10.1186/cc7693) This article is online at: /content/13/1/R4 ? 2009 Haberthür et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction The effect of expiratory endotracheal tube (ETT) Results At a given test lung compliance, inspiratory pressure and ETT size, increasing respiratory rates from 15 to 30/minutes had the following effects: inspiratory tidal volume and peak expiratory flow were decreased by means of 25% (range 0% to 51%) and 11% (8% to 12%), respectively; and trapped lung volume and intrinsic PEEP were increased by means of 25% (0%