Feeding and fasting controls liver expression of a regulator of G protein signaling (Rgs16) in periportal hepatocytes.docVIP

下载本文档

1
0
约5.24万字
约 11页
2017-05-16 发布于上海
举报
版权申诉

Feeding and fasting controls liver expression of a regulator of G protein signaling (Rgs16) in periportal hepatocytes.doc

1、本文档共11页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
8、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Feeding and fasting controls liver expression of a regulator of G protein signaling (Rgs16) in periportal hepatocytes

Comparative Hepatology BioMedCentral Research Open Access Feeding and fasting controls liver expression of a regulator of G protein signaling (Rgs16) in periportal hepatocytes Jie Huang1, Victor Pashkov1, Deborah M Kurrasch1,2, Kan Yu1,3, Stephen J Gold4,5 and Thomas M Wilkie*1 Address: 1Department of Pharmacology, UT Southwestern Medical Center, 6001 Forest Park Dr., Dallas TX 75390-9041, USA, 2Department of Physiology, University of California, San Francisco 94143-2611, USA, 3Department of Neurology, University of Mississippi Medical Center, Jackson MS 39216, USA, 4Department of Psychiatry, UT Southwestern Medical Center, 6001 Forest Park Dr., Dallas TX 75390-9070, USA and 5Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Blvd., Ft. Worth TX 76107, USA Email: Jie Huang - Jie.Huang@UTS; Victor Pashkov - Victor.Pashkov@UTS; Deborah M Kurrasch - Deborah.Kurrasch@; Kan Yu - Kanyu@; Stephen J Gold - sgold@; Thomas M Wilkie* - Thomas.Wilkie@UTS * Corresponding author Published: 23 November 2006 Received: 07 May 2006 Accepted: 23 November 2006 Comparative Hepatology 2006, 5:8 doi:10.1186/1476-5926-5-8 This article is available from: /content/5/1/8 ? 2006 Huang et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Heterotrimeric G protein signaling in liver helps maintain carbohydrate and lipid homeostasis. G protein signaling is activated by binding of extracellular ligands to G protein coupled receptors and inhibited inside cells by regulators of G protein signaling (RGS) proteins. RGS proteins are GTPase activating proteins, and thereby regulate Gi and/or Gq class G proteins. RGS gene expression can be induced by the ligand