The pharmacological note (the test version) is matched(国外英文资料).docVIP

The pharmacological note (the test version) is matched(国外英文资料) Pharmacology of notes Efferent nervous system pharmacology One, anatomical knowledge: efferent neurotransmitter classification includes: Adrenalin: sympathetic nerves Cholinergic nerve: parasympathetic and somatic motor nerve Efferent neural effector, the distribution of receptors and their effects Adrenalin can be excited: it ACTS on the B1 receptor on the heart, which makes the heart rate faster, conducts fast, and shrinks. A receptor that ACTS on the mucosa of the skin and the internal organs of the abdominal cavity, causing it to contract; A B2 receptor that ACTS on the broncho-smoothing machine, making it diastolic. The function of the eye pupil sphincter a receptor, causes it to contract 2, cholinergic nerve excitement: role in bronchial smooth muscle, gastrointestinal smooth muscle, pupillary sphincter, ciliary muscle of M receptor, make its shrinkage: role in skeletal muscle of N2 receptors, make it shrink Quasi choline medicine 1, the direct effects on choline receptor choline medicine, direct M excited choline receptor quasi choline medicine: jaborandi alkali, high selectivity of the product in the eyes smooth muscle, thus causing shrinkage, reduce intraocular pressure, adjust the pupil convulsion, clinical effect in ophthalmology, glaucoma, iridocyclitis) Echoline-anticholinesterase agent: the Ming of the new (1) action mechanism: the contravariant inhibition of cholinesterase activity shows the role of cholinergic acid (2) use: excited skeletal muscle, treatment of the myasthenia: excitatory gastrointestinal and bladder smooth muscle treatment after postoperative abdominal bloating and urinary retention Organophosphorus poisoning and rescue Organic phosphate ester (1) poisoning mechanism: refers to the pesticide, it is combined with cholinesterase into hard to hydrolysis of phosphorus acylation choline enzyme, such as rescue is not timely, poisoning enzyme will be aging, lose their activity,