血小板削减(国外英文资料).docVIP

血小板减少(国外英文资料) Pregnancy with thrombocytopenia is one of the common blood system during pregnancy complications, including pregnancy associated thrombocytopenia (pregnancy - associated thrombocytopenia, PAT), also known as gestational thrombocytopenia (gestational thrombocytopenia, GT), the main reason for its, accounts for about 65% ~ 80% [1]. PAT that occurred for the first time in the late in pregnancy, of mild thrombocytopenia ( 70 x 109 / L), usually asymptomatic and more than 12 weeks postpartum recovery of its own, is regarded as a benign self-limited, blood system diseases during pregnancy. Depending on the level of platelets, they can be classified as mild (100 ~ 150 x 109 / L), moderate (50 ~ 100 x 109 / L) and severe ( 50 x 109 / L). It has no history of thrombocytopenia during pregnancy, usually associated with postpartum haemorrhage and fetal thrombocytopenia, but can be relapsed after pregnancy. Because there is currently no specific laboratory diagnostic criteria, the diagnosis is an exclusion diagnosis, which excludes other diseases and the reduction of platelets caused by drugs. The etiology and pathologic mechanism of thrombocytopenia in pregnancy PAT occurrence mechanism is still unclear, most scholars think: pregnancy pregnant women blood volume increase physiological and hemodilution, due to the high coagulation state of loss and increase in the number of collection and use of platelets in the placental circulation, lead to less platelet, rather than increased platelet destruction, so it is possible that PAT is a normal physiological phenomenon in pregnancy. Verdy and [2] observe that the level of platelets decreases with the increase of gestational age during pregnancy without complications, and by about 10 percent in the late trimester. Tsunoda, etc. [3] the study found that at the same time, twin pregnancy compared with single pregnancy pregnant women, on average, low platelet count, may be due to the twin pregnancy pregnant women blood volum