孔祥成说不合年纪段的运动神经元发病症状不合(国外英文资料).docVIP

孔祥成说不同年龄段的运动神经元发病症状不同(国外英文资料) Kong xiang cheng said that motor neurons in different age groups have different symptoms Motor neurone disease (MND) is a group of chronic progressive diseases, primarily in the anterior horn of the spinal cord, the nucleus of the cranial nerve and the pyramidal tract. Symptoms such as muscle atrophy and muscle weakness are the most common. If you have difficulty speaking, difficulty swallowing, difficulty in activity, difficulty in breathing, etc. At the end of the patients consciousness, he died of inability to breathe. So this kind of patient is also called frozen person. According to the area of the most severely damaged nervous system, clinical symptoms vary depending on the location of the lesion. ALS (ALS) The most common. The onset of onset is between 40 and 50 years of age, with more men than women. Slow progress in the form of disease. Clinical symptoms tend to start in the upper extremity, which is characterized by atrophy of the muscles of the hand and the inability of the muscles to move towards the forearm, upper arms and shoulder blades. Atrophy muscles have obvious muscle pulsations; The lower extremities are paralyzed by motor neurons, which are characterized by increased muscle tone, hyperreflexia and pathological signs. Symptoms usually develop from one side to the other. Fundamental symmetry damage. With the development of the disease, the symptoms of nuclear damage of the neuromuscular nerve movement of the bridge are gradually developed, and the lingual muscle atrophy, the difficulty of swallowing and the ambiguity of speech. The late influence of the muscle and breathing muscles. ALS major clinical features: upper and lower motor neurons simultaneously damage. Progressive spinal muscle atrophy The lesions are confined to the anterior horn of the spinal cord and do not affect motor neurons. This type can be divided according to the age of the disease and the lesion: (1) adult (remote) : occurs in middle-aged men,