ExPASy： the proteomics server for in-depth.pdfVIP

3784–3788 Nucleic Acids Research, 2003, Vol. 31, No. 13 DOI: 10.1093/nar/gkg563 ExPASy: the proteomics server for in-depth protein knowledge and analysis * Elisabeth Gasteiger , Alexandre Gattiker, Christine Hoogland, Ivan Ivanyi, Ron D. Appel and Amos Bairoch ´ Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel Servet, 1211 Geneva 4, Switzerland Received February 18, 2003; Revised and Accepted April 2, 2003 ABSTRACT put at the disposal of the users different expert views of the complex world of biological data and knowledge. The ExPASy (the Expert Protein Analysis System) World Wide Web server (), is provided as a service to the life science community by DATABASES a multidisciplinary team at the Swiss Institute of Bioinformatics (SIB). It provides access to a variety ExPASy (1,2) is the main host for the following databases that are partially or completely developed at the SIB in Geneva: of databases and analytical tools dedicated to proteins and proteomics. ExPASy databases include SWISS- The SWISS-PROT knowledgebase (3,4) (http://www. /sprot/) is a curated protein sequence database, PROT and TrEMBL, SWISS-2DPAGE, PROSITE, which strives to provide high quality annotations (such as ENZYME and the SWISS-MODEL repository. Analysis