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微静脉白细胞流淌散布的影响成分及其在掉血性休克时的变更(国外英文资料)
微静脉白细胞流动分布的影响因素及其在失血性休克时的变化(国外英文资料)
The influencing factors of the flow distribution of microbiocyte and its changes in the hemorrhagic shock
Update date: 2011-07-22 jiang yong liu ai hua
One, material and method
Twenty SD rats, male and female, were randomly divided into the normal control group and the hemorrhagic shock group, 10 per group. With the mass fraction of 13.3% urethane (urethane) plus the mass fraction of 1% chloralose chloralose) anesthesia (6 ml/kg, muscle injection), copy severe uncontrolled hemorrhagic shock rats model, to observe and record the change of the mesenteric microcirculation [1, 2]. The diameter of the vessel (D) was measured by the microcirculation image multiparameter computer analysis system (MIMPCAS). Red blood cell velocity (Vrbc), visible white blood flow velocity (VLV), visible white blood cell flux (VLF), the method of measurement is known as [2]. The experimental data showed that the difference was significant by using the Students t test.
Second, the results
1. Uncontrolled hemorrhagic shock of blood vessel diameter and the influence of white blood flow distribution curve: choose the blood flow velocity of 1.2 mm/s or so, diameter distribution range of 10 ~ 50 microns micro vein, the research and the relationship between white blood flow distribution and the diameter of blood vessels. In physiological conditions, large diameter vessels, VLF are also higher; When the diameter of the vessel increases from 10 mu m to 50 mu m, VLF also increases from 3.6 cells/min to 28.2 cells/min. In the late stage of the hemorrhagic shock, the relationship curve was significantly removed, indicating a significant reduction in the white blood cells rolling along the wall of the mesenteric microvein. The diameter of the vessel has no significant effect on VLV. Normally, VLV in the microvein is maintained at 25 ~ 30 mu m/s. In the late stage of the hemorrhagic shock, the blood vessel diameter and VLVs relationship curve clearly shifted down, and
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