白舒非(白消安打针液)(国外英文资料).docVIP

白舒非(白消安注射液)(国外英文资料) White shudnon (white antian injection) 【 drug name 】 Product name: baishu Generic name: white antiampere injection English name: Busulfan Injection 【 composition 】 1, 4-butyl glycol dimethyl sulfonate 【 indications 】 It is mainly applicable to the slow period of chronic myelogenous leukemia, which is not good for patients lacking Philadelphia chromosome Ph1. It can also be used in the treatment of primary thrombocytopenia and chronic myelogenous diseases such as hypertropism. [usage] Oral: adults 2-8mg per day, children 0.05 mg per kg. Until the white blood cells are down to 10,000 to 20,000 and then stop or change to the amount of maintenance (0.5 ~ 2mg, 1 time per day or 2 times per week). With intermittent high-dose treatment of chronic myelogenous leukemia, curative effect and method on basic same, but can shorten the induction time, and may decrease the chance of aplastic anemia. Usage is: according to patients white blood cell and platelet counts, choose one for 80-100 mg, 50 mg, 20-30 mg of three different doses (if one take 100 mg, general points 2 times, internal and finished in 1 ~ 2). The interval between the two doses is one to two weeks (depending on the blood image), and if you take the pill 80 to 100 mg, it will take more than two weeks. [adverse reaction] It can cause bone marrow suppression. It is common for granulocytes to be reduced and platelets decreased. Serious people need to stop medicine in time. Long-term use or drug overuse can cause pulmonary fibrosis. Can have skin pigmentation composed, hyperuric acidemia and sexual function decline, male breast is feminine, testicular atrophy, female menstruation is not adjusted and so on. Cataract, polytype erythema rash, nodular polyarteritis is a rare adverse reaction. There have been individual reports of epileptic seizures following high doses; The endocardial fibrosis and the resulting symptoms; And rare hepatic veins are closed. 【 taboo 】 This product may increase the risk o