经皮冠状动脉腔内成形术前后血小板功效及前列腺素水平的变更及其临床意义(国外英文资料).docVIP

经皮冠状动脉腔内成形术前后血小板功能及前列腺素水平的变化及其临床意义(国外英文资料) Changes in the function of platelet function and prostaglandin level and its clinical significance after percutaneous coronary angioplasty The 2011-01-17 Ma yingyan jia zhang yu-shun guo wenyi zhang qing Liu bing li yuan wang xiaoyan li LAN sun 【 abstract 】 objective to study the patients with coronary heart disease (CHD) percutaneous coronary artery lumen angioplasty (PTCA), before and after the change of platelets in the coronary circulation, provide reference for clinical medication. Methods by coronary sinus blood, put free method after PTCA preoperative platelet surface test of alpha particles membrane protein (GMP - 140) number of molecules and plasma thromboxane B2 (TXB2), plasma 6 - ketone - alpha prostaglandin F1 (6 - ketone - PGF1 alpha) concentration. Results 23 cases of stable angina pectoris patients, 15 cases of unstable angina pectoris patients after PTCA GMP - 140 and 5 minutes platelet membrane surface plasma TXB2 increased obviously, reached a peak after 10 minutes, 30 minutes down to normal. Conclusion the patients with coronary heart disease have platelet activation after operation. 【 keywords 】 angioplasty, by the cavity, trancutaneous coronary artery platelet prostatin F The clinical significance of The change in platelet function and prostaglandin level with PTCA MA Yingyan, JIA Guoliang, ZHENG Changzhu, et al. Xi Jing Hospital, Fourth Military Medical University, The PLA, Xian 710032 【Abstract】　Objective　To observe the active change of the platelet in the coronary circulation before and after PTCA in the patients with coronary heart disease in order to provide a guide to clinical drug usage. Methods　Blood was obtained from the coronary sinus. Molecular amount of CMP-140 on the surface of platelet and concentration of TXB2, 6-keto-PGF1α in plasma were determined using radioimmunoassay. Results　Both the amount of GMP-140 and the concentration of TXB2 were higher after PTCA than those before PTCA, risi