基于希尔伯特_黄变换地近红外脑功能成像信号分析_周振宇.pdfVIP

27 2 Vol. 27,No. 2 2007 2 ACTA OPTICA SINICA February, 2007 : 0253-2239(2007)02-0307-6 基于希尔伯特 黄变换的近红外脑功能成像信号分析* 1,2 1 3 3 1,2 周振宇 杨宏宇 龚 辉 骆清铭 陆祖宏 1 , 210096 2 , 210096 3 , 430074 : ( Near-infrared spectroscopy, NIRS), , , ( ilbert- uang transform, T) , , : ; ; ; : T P274. 52 : A Brain Signal Analysis of Functional Near-infrared Imaging Based on Hilbert-Huang Transform 1,2 1 3 3 1,2 Zhou Zhenyu Yang Hongyu Gong Hui Luo Qingming Lu Zuhong 1Research Centre of Lear ning Science, Southeast University , Nanjing 210096 2 School of Biological Science and Medical Engineering, Southeast Univer sity , Nanj ing 210096 3 Key Laboratory of Biomedical Photonics, Ministray of Education , uazhong Univer sity of Science and Technology , Wuhan 430074 Abstract: Near-infrared spectroscopy (NIRS) has een widely used to access the rain functional activity non- invasively, ut traditional signal analysis methods are unsuita le for non-linear and non-stationary data. A novel signal processing method is developed y using Hil ert-Huang transform (HHT) to perform spectral analysis of functional NIRS signals sampled in avision stimulation experiment ased on event-related design. Compared with wavelet ased multi-resolution analysis (MRA) and Fourier spectral analysis, we demonstrate that the HHT method is etter in the extraction of task related signal for o servation of activation in the prefrontal cortex. Th