GenBANK介绍及使用说明.pdf

D36–D42 Nucleic Acids Research, 2013, Vol. 41, Database issue Published online 27 November 2012 doi:10.1093/nar/gks1195 GenBank Dennis A. Benson, Mark Cavanaugh, Karen Clark, Ilene Karsch-Mizrachi, David J. Lipman, James Ostell and Eric W. Sayers* National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA Received September 28, 2012; Revised and Accepted October 29, 2012 ABSTRACT sequence (GSS), whole-genome shotgun (WGS) and GenBank () is a com- other high-throughput data from sequencing centres. The U.S. Patent and Trademark Office also contributes prehensive database that contains publicly available sequences from issued patents. GenBank participates with nucleotide sequences for almost 260 000 formally the European Molecular Biology Laboratory Nucleotide D described species. These sequences are obtained Sequence Database (EMBL-Bank), part of the European o primarily through submissions from individual Nucleotide Archive (ENA) (2), and the DNA Data Bank w n