清消合剂促进低位单纯性肛瘘术后伤面愈合的临床分析.pdfVIP

摘 要 摘 要 目的：通过观察低位单纯性肛瘘术后伤面愈合过程，评价清消合剂对伤面愈合时 间、伤面疼痛、伤面成纤维细胞数目的影响。探讨该药促进伤面愈合的科学依据。 方法：将 2010 年 4 月至2010 年 12 月符合纳入标准的低位单纯性肛瘘患者60 例 按入院先后顺序分为：治疗组30 例，术后温服清消合剂配合常规换药；对照组 30 例，单纯常规换药。治疗后观察患者伤面恢复情况，另分别从治疗组和对照组随 机抽出20 例于 7、12 天取伤面肉芽组织作病理切片分析，观察伤面成纤维细胞数 目。通过此项研究，比较两组患者伤面愈合时间、疼痛情况、成纤维细胞数目情 况。 结果：清消合剂治疗组伤面愈合时间较单纯换药对照组平均提前 2 天，具有显著 性差异 （P ﹤0.05）。同时研究发现，本品可有效地缓解临床伤面疼痛（P ﹤0.05）， 并提高伤面肉芽组织成纤维细胞的数目（P ﹤0.05）， 结论：清消合剂对肛肠病术后伤面有良好的促愈作用。它能缓解伤面疼痛，促进 伤面肉芽组织成纤维细胞的增生，以达到缩短伤面愈合的时间。 关键词：清消合剂；低位单纯性肛瘘；伤面愈合时间；疼痛；成纤维细胞 - 1 - 清消合剂促进低位单纯性肛瘘术后伤面愈合的临床研究 Research on the Effects and Mechanism of Qingxiaoheji to Postoperative Wound Healing of Patients with Simple low Anal Fistula Wang Qing (Surgery of Traditional Chinese Medicine) Directed by Liu Dianwen Abstract Objective : By observing the low anal fistula during wound healing process, evaluat e Qingxiaoheji on wound healing time, wound pain, bleeding, the number of wound fibroblasts and inflammatory response of wound, discuss the scientific basis of drug to promote wound healing. Methods : According to the or der that they were admitted to hospital from April 2010 to December 2010 ,60 patients with simple low anal fistula who fitted the diagnostic standards in the study were enrolled and divided into two groups randomly, The treatment group of 30 patients, taki ng Qingxiaoheji together with conventional dressing after surgery; the c ontrol group of 30 patients, receiving conventional dressing. After treatment, observe in patients with wound recovery . Respectively selected 20