supplementarymaterials–markusetal.docVIP

Supplementary Materials – Markus et al. Quantitative Analysis of Pac1/LIS1-mediated Dynein Targeting: Implications for Regulation of Dynein Activity in Budding Yeast SUPPLEMENTARY NOTE 1 Mixture of normals in data sets. Using the Mclust package for R (Fraley and Raftery 2007) we found the data sets of several dynein pathway components to fit better to a mixture of two normals rather than a single normal distribution. Specifically, the data sets for plus end-associated Dyn1, Dyn3, Pac11, Pac1 and Jnm1, and cortically-associated Dyn1 and Pac11 were all fit better by two components according to t