1352例狼疮性肾炎的临床和免疫学特征_胡伟新.pdfVIP

15 5 2006 10 # 401# # # 1352 胡伟新 刘春蓓 孙海鸥 刘正钊 谢红浪 章海涛 陈惠萍 曾彩虹 刘志红 黎磊石 目的: 1 352( LN ) 方法: 1986 2005 LN 1 352 2003 ISN/RPS, + + , 结 : 1 352, 1 193 ( 8812% ), 159( 1118% ), 8~ 60[ ( 2713? 912) ], 18~ 50 80% 4911%, 1414% 141 2%+ 1117% 516% + 51 0% , ( 591 7% vs 4716%, P 0101) : , , -dsDN ;, ( NC )( 1013% ), -dsDN C4 , -dsDN C4 + , ( 5216% vs 3116% ), NC ( 51 7% vs 0) + , , NC C4 LN, ( 3411%, 3418%, 3216% ) 结论: LN , , + LN ,, Clinical and imm unologica l features of 1 352 Chinese patients w ith lupus nephritis H U Weixin, LIU Chunbei, SUN H aiou, LIU Zhengzhao, X IE Honglang, ZHANG Haitao, CHEN Hupi ing, ZENG Caihong, LIUZhihong, LI L eishi esearch Institute of Nephrology, Jingling Hosp ital, Nanjing University School of M ed icine, Nanj ing 210002, China ABSTRACT Objecti e: To analyze the clinical and mi munological features of 1 352 Chinese patientswith lupus ne- phritis in a single-center. M ethodology: 1 352 LN patients in Jingling Hospital from 1986 to 2005 were included in this study. llpatients had renalbiopsy. The histologicalclassificationswere categorized according to 2003 ISN/RPS classifica- tion (Class and were not included in the study). The cmbined class of or and were recorded as + or + . R esults: 1 193 ( 8812% ) females, and 159( 1118% ) maleswere allHan Chinese, 80% of them were from 18 to 50 years old (mean 271 3? 91 2 years) . The renal histological classes showed class ( 1412% ), ( 516% ), ( 4911% ), ( 1414% ), + ( 1117% ) and + ( 5% ). The proportion of class ( 1512% ) and ( 612% ) in females was higher than that inmales ( 619