第二节 脂肪的分.pptVIP

FIGURE 17–17 The oxidation of a branched-chain fatty acid (phytanic acid) in peroxisomes. Phytanic acid has a methyl-substituted carbon and therefore cannot undergo oxidation. The combined action of the enzymes shown here removes the carboxyl carbon of phytanic acid, to produce pristanic acid, in which the carbon is unsubstituted, allowing oxidation. Notice that oxidation of pristanic acid releases propionyl-CoA, not acetyl-CoA. This is further catabolized as in Figure 17–11. (The details of the reaction that produces pristanal remain controversial.) * * * * * * FIGURE 17–20 Ketone b