【2017年整理】Book与2Unit4TextA.doc

Unit 4 Gene and Disease Text A Hyperactive Children May Suffer from Genetic Disorder 1 Report claims ADHD could be more of a neurodevelopmental condition than a behavioural problem 2 Ritalin is widely used to treat children diagnosed with ADHD. 3 Parents of hyperactive children should not be blamed for failing to bring up their offspring properly, according to scientists who today publish evidence that the condition is genetic. 4 Children with attention deficit hyperactivity disorder (ADHD) find it hard to concentrate and can be wild and uncontrollable both at home and at school. Controversy has raged around the drug most widely used to calm such children, Ritalin, which is of the amphetamine family. In the US, such drugs became popular among families who wanted their lively (non-ADHD) boys to do better in class, while in the UK they were tagged chemical coshes. Meanwhile, parents have often tacitly been blamed for lack of discipline or giving their children a sugar and additive-laden diet. 5 But today the furore around ADHD moves into a different space. Researchers, funded not by drug companies but by the Wellcome Trust and other bodies, are publishing the results of a study which for the first time identifies genetic changes in children diagnosed with ADHD. 6 And the particular DNA markers they found are in the same area of the brain as genetic variants linked to autism and schizophrenia. That means, say the authors of the paper in the Lancet, that ADHD would be better classified as a neurodevelopmental disorder than a behavioural problem. 7 “We hope that these findings will help overcome the stigma associated with ADHD,” said Professor Anita Thapar from the MRC Centre in Neuropsychiatric Genetics and Genomics at Cardiff University, one of the authors. 8 “Too often, people dismiss ADHD as being down to bad parenting or poor diet. As a clinician, it was clear to me that this was unlikely to be the case. Now we can say with confidence that ADHD is a geneti